PENTAVITIN®
Patented by DSM Personal Care
INCI name: Saccharide Isomerate
A patented, 100% natural ingredient. A saccharide compound, similar in its composition to the mixture found in our body, so that it is recognized and treated by the skin as a noninvasive agent. Pentavitin® absorbs fluids in order to fill up skin cells and to retain a fixed, optimal supply. Proven by research to sooth the skin 50% more than the acceptable levels found in glycerin. This active ingredient treats flaky skin, irritations and rashes in the most effective manner.
• Unique composition similar to that of the carbohydrate complex (NMF) found in human skin
• Derived from plant based D-glucose
Unique binding ensures a mechanism for deep hydration
• Unique binding mechanism to the skin that is not washed off
• The removal of PENTAVITIN® occurs only by the natural process of desquamation
• Proven binding to amino acid lysine (free ε-amino groups) at the corneocytes
Deep hydration for 72 hours
1% PENTAVITIN® reduces signs of dry skin by 20% after 4 weeks according to Kligman’s clinical grading. After the last treatment the effects of PENTAVITIN® last for 72 hours.
Strengthens skin barrier function
1% PENTAVITIN® strengthens skin barrier function shown by 20% reduction in TEWL before and after
20 subsequent tape stripping after a 28 day application.
in vivo Efficacy – 14-day hydration
5% PENTAVITIN® outperforms 5% glycerin significantly after a 14-day application
By 43% more hydration on dry skin and
By 42% more hydration on normal skin
Improves a comfortable skin feeling & a healthy skin appearance
Confirmations of Consumer panel testing after 2 weeks of 1% PENTAVITIN®
• Improves skin softness and smoothness by more than 50%
• Reduces flakiness by more than 50%
• Reduces itchiness by more than 50% and tightening by more than 30%
• Improves skin robustness by more than 20%
in vivo Efficacies – Study details
Anti-Irritant test:
- 12 female volunteers, aged 40 to 60 with normal to dry and slightly sensitive skin
- Formulation containing 5% AHA (lactic acid) with and without 5% PENTAVITIN®, pH 3.0
- Application on the left and right sides of their faces, during four weeks
- Measurements at day 0, 5, 10, 15, 20, 25 and day 28
- Efficacy evaluated with stinging scores
PENTAVITIN® reduces AHA induced irritation
by approximately 22 % after 28 days
